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. 2010 Oct 28;6(10):e1000972. doi: 10.1371/journal.pcbi.1000972

Table 2. Calcium and buffer reaction-diffusion parameters.

Symbol Definition Value Ref.
Ca2+ and buffer concentrations
Inline graphic Extracellular Ca2+ concentration 1000 µM [33]
Inline graphic Resting Ca2+ concentration 0.1 µM [33]
Inline graphic Total Fluo-3 concentration 100 µM [18]
Inline graphic Total free ATP concentration 260 µM [18]
Inline graphic Total troponin concentration 70 µM [18]
Inline graphic Total calmodulin concentration 24 µM [18]
Diffusion coefficients (at 22°C)
Inline graphic Diffusion coefficient for Ca2+ 0.39 µm2 ms−1 [18]
Inline graphic Diffusion coefficient for CaFluo 0.1 µm2 ms−1 [18]
Inline graphic Diffusion coefficient for CaATP 0.168 µm2 ms−1 [18]
Inline graphic Diffusion coefficient for CaCal 0.025 µm2 ms−1 [18]
Rate coefficients and dissociation constants (at 22°C)
Inline graphic Ca2+ on-rate constant for TN 0.04 µM−1 ms−1 [19]
Inline graphic Ca2+ off-rate constant for TN 0.04 ms−1 [19]
Inline graphic Ca2+ dissociation constant for TN 1 µM [19]
Inline graphic Ca2+ on-rate constant for CaATP 0.225 µM−1 ms−1 [18]
Inline graphic Ca2+ off-rate constant for CaATP 45 ms−1 [18]
Inline graphic Ca2+ dissociation constant for ATP 200 µM [18]
Inline graphic Ca2+ on-rate constant for CaFluo 0.23 µM−1 ms−1 [18]
Inline graphic Ca2+ off-rate constant for CaFluo 0.17 ms−1 [18]
Inline graphic Ca2+ dissociation constant for Fluo 0.739 µM [18]
Inline graphic Ca2+ on-rate constant for Cal 0.125 µM−1 ms−1 [18]
Inline graphic Ca2+ off-rate constant for Cal 0.2975 ms−1 [18]
Inline graphic Ca2+ dissociation constant for Cal 2.38 µM [18]