Ca2+ and buffer concentrations
|
|
Extracellular Ca2+ concentration |
1000 µM |
[33]
|
|
Resting Ca2+ concentration |
0.1 µM |
[33]
|
|
Total Fluo-3 concentration |
100 µM |
[18]
|
|
Total free ATP concentration |
260 µM |
[18]
|
|
Total troponin concentration |
70 µM |
[18]
|
|
Total calmodulin concentration |
24 µM |
[18]
|
Diffusion coefficients (at 22°C)
|
|
Diffusion coefficient for Ca2+
|
0.39 µm2 ms−1
|
[18]
|
|
Diffusion coefficient for CaFluo |
0.1 µm2 ms−1
|
[18]
|
|
Diffusion coefficient for CaATP |
0.168 µm2 ms−1
|
[18]
|
|
Diffusion coefficient for CaCal |
0.025 µm2 ms−1
|
[18]
|
Rate coefficients and dissociation constants (at 22°C)
|
|
Ca2+ on-rate constant for TN |
0.04 µM−1 ms−1
|
[19]
|
|
Ca2+ off-rate constant for TN |
0.04 ms−1
|
[19]
|
|
Ca2+ dissociation constant for TN |
1 µM |
[19]
|
|
Ca2+ on-rate constant for CaATP |
0.225 µM−1 ms−1
|
[18]
|
|
Ca2+ off-rate constant for CaATP |
45 ms−1
|
[18]
|
|
Ca2+ dissociation constant for ATP |
200 µM |
[18]
|
|
Ca2+ on-rate constant for CaFluo |
0.23 µM−1 ms−1
|
[18]
|
|
Ca2+ off-rate constant for CaFluo |
0.17 ms−1
|
[18]
|
|
Ca2+ dissociation constant for Fluo |
0.739 µM |
[18]
|
|
Ca2+ on-rate constant for Cal |
0.125 µM−1 ms−1
|
[18]
|
|
Ca2+ off-rate constant for Cal |
0.2975 ms−1
|
[18]
|
|
Ca2+ dissociation constant for Cal |
2.38 µM |
[18]
|