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. 2010 Oct 28;6(10):e1001161. doi: 10.1371/journal.ppat.1001161

Figure 7. Retention and loss of RNAi machinery and activity during trypanosomatid evolution.

Figure 7

A consensus evolutionary tree is shown; the scale corresponds to the degree of evolutionary divergence amongst these organisms (Fig. 6). Lineages lacking RNAi activity and/or genes are indicated at the termini, with RNAi-deficient lineages colored red and RNAi-proficient lineages colored blue. Bicoloring along the T. cruzi lineage signifies that the point at which RNAi was lost is unknown. The + or − symbols indicate the presumptive presence and/or loss of RNAi during evolution.