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. 2010 Oct 28;6(10):e1001168. doi: 10.1371/journal.ppat.1001168

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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HPIV3 HN/F (A) or NiV G/F (B) co-expressing cells were allowed to fuse with sialic acid receptor-bearing cells (293T) in the presence of increasing concentrations of VIKI-PEG₄-chol (circle), V-PEG₄-chol (triangle) or V-chol (square) peptide. After 4 hours, the amount of fusion was quantitated using a beta-galactosidase complementation assay as described in Materials and Methods. The percent inhibition of fusion (compared to results for control cells not treated with peptide) is shown as a function of the (log-scale) concentration of peptide. The values are means (± SD) of results from three experiments.