Monte Carlo simulations for bi-component T2* fitting: long T2*=(30ms, 75%), short T2* =(1/2/3ms, 25%); SNR (at TE=0ms) =286 (noise_1), 143 (noise_2) or 95 (noise_3); noise trials=500; Type-1 (9-TE) (ms) = (0.5, 1.5, 3.0, 4.5, 7, 10, 20, 30, 40), Type-2 (11-TE) (ms) = (0.5, 1, 2, 3, 4, 5, 7, 10, 20, 30, 40).
a-c) For short T2* at 1, 2, and 3ms, Type-2 (11-TE) produced smaller SD values than Type-1 (9-TE) when T2* became shorter from 3 to 1ms.
d-e) For a long T2* at 30ms, the SD values are less than 7% at all the three SNR levels for both Type-1 and Type-2. Note: in c) the mean and SD at noise_3 were excluded due to large SD value.