Table 1. The relationship between clinicopathological characteristics and cancer-specific survival in patients undergoing surgery for Dukes B colon cancer: univariate and multivariate analysis.
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| Risk factor | Patients (n=920) | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value |
| Age (<75/⩾75 years) | 562/358 | 1.43 (1.14–1.79) | 0.002 | 1.45 (1.15–1.82) | 0.001 |
| Sex (female/male) | 493/427 | 1.22 (0.98–1.53) | 0.081 | ||
| Deprivationa (intermediate) | 164/589/166 | 1.15 (0.85–1.57) | 0.369 | ||
| (deprived) | 1.06 (0.72–1.56) | 0.780 | |||
| Mode of presentation (elective/emergency) | 592/328 | 1.58 (1.26–1.98) | <0.001 | 1.59 (1.27–1.99) | <0.001 |
| Specialisation (yes/no) | 197/700 | 1.19 (0.89–1.59) | 0.241 | ||
| Anastomotic leak (no/yes) | 896/24 | 2.11 (1.21–3.67) | 0.009 | 2.17 (1.24–3.78) | 0.006 |
| Adjuvant therapy (no/yes) | 811/14 | 0.76 (0.28–2.03) | 0.577 |
Abbreviation: CI=confidence interval.
a
Baseline – affluent.
Baseline variables/comparison group in brackets after risk factor.