Table 3. The relationship between clinicopathological characteristics and overall survival in patients undergoing surgery for Dukes B colon cancer: univariate and multivariate analysis.
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| Patients (n=920) | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | |
| Age (<75/⩾75 years) | 562/358 | 2.13 (1.81–2.49) | <0.001 | 2.15 (1.84–2.52) | <0.001 |
| Sex (female/male) | 493/427 | 1.26 (1.07–1.47) | 0.005 | 1.30 (1.11–1.52) | 0.001 |
| Deprivationa (intermediate) | 164/589/166 | 1.22 (0.97–1.52) | 0.089 | ||
| (deprived) | 1.28 (0.98–1.67) | 0.076 | |||
| Mode of presentation (elective/emergency) | 592/328 | 1.41 (1.20–1.65) | <0.001 | 1.44 (1.22–1.69) | <0.001 |
| Specialisation (yes/no) | 197/700 | 0.92 (0.76–1.11) | 0.362 | ||
| Anastomotic leak (no/yes) | 896/24 | 1.56 (0.99–2.46) | 0.057 | ||
| Adjuvant therapy (no/yes) | 811/14 | 0.48 (0.22–1.08) | 0.077 |
Abbreviation: CI=confidence interval.
a
Baseline – affluent.
Baseline variables/comparison group in brackets after risk factor.