Table 4. The relationship between clinicopathological characteristics and overall survival in patients undergoing surgery for Dukes B rectal cancer: univariate and multivariate analysis.
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| Patients (n=430) | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | |
| Age (<75/⩾75 years) | 302/128 | 2.26 (1.78–2.85) | <0.001 | 2.20 (1.74–2.79) | <0.001 |
| Sex (female/male) | 186/244 | 1.12 (0.89–1.41) | 0.324 | ||
| Deprivationa (intermediate) | 65/260/105 | 1.18 (0.84–1.64) | 0.345 | ||
| (deprived) | 1.22 (0.84–1.77) | 0.300 | |||
| Mode of presentation (elective/emergency) | 364/66 | 1.47 (1.09–1.97) | 0.011 | 1.30 (0.97–1.75) | 0.084 |
| Specialisation (yes/no) | 122/299 | 1.04 (0.80–1.34) | 0.779 | ||
| Anastomotic leak (no/yes) | 409/21 | 1.08 (0.64–1.81) | 0.777 | ||
| Adjuvant therapy (no/yes) | 348/22 | 1.16 (0.69–1.95) | 0.589 |
Abbreviation: CI=confidence interval.
a
Baseline – affluent.
Baseline variables/comparison group in brackets after risk factor.