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. 2010 Sep 7;103(7):987–992. doi: 10.1038/sj.bjc.6605867

Table 3. Principal JNJ-26483327-related side-effects.

  100 mg (n=1)
200 mg (n=1)
400 mg (n=1)
800 mg (n=3)
1200 mg (n=3)
1500 mg (n=6)
2100 mg (n=4)
Total (n=19)
  G 1/2 G 3/4 G 1/2 G 3/4 G 1/2 G 3/4 G 1/2 G 3/4 G 1/2 G 3/4 G 1/2 G 3/4 G 1/2 G 3/4 n %
Nausea 0 0 0 0 1 0 2 0 3 0 6 0 1 0 13 68.4
Diarrhoea 0 0 1 0 1 0 2 0 2 0 3 1 2 0 12 63.2
Rash 1 0 1 0 0 0 2 0 1 0 3 1 2 0 11 57.9
Vomiting 0 0 0 0 1 0 2 0 2 0 3 0 2 0 10 52.6
Fatigue 1 0 0 0 0 0 1 0 1 0 3 0 2 1 9 47.4
Anorexia 0 0 0 0 0 0 1 0 1 0 3 0 1 2 8 42.1
Anaemia 0 0 1 0 1 0 0 0 1 0 0 0 0 0 3 15.8
Dysphonia 0 0 0 0 0 0 0 0 1 0 2 0 0 0 3 15.8
Pain 0 0 0 0 1 0 0 0 1 0 0 0 0 0 2 10.5
Dry skin 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 10.5
Constipation 0 0 0 0 0 0 0 0 1 0 1 0 0 0 2 10.5
Weight decreased 0 0 0 0 0 0 1 0 0 0 0 0 1 0 2 10.5
Dyspepsia 0 0 0 0 0 0 0 0 1 0 1 0 0 0 2 10.5
Dry skin 0 0 0 0 0 0 0 0 0 0 2 0 0 0 2 10.5
Skin exfoliation (palms) 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 5.3
Skin discolouration 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 5.3