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. 2010 Nov 3;99(9):3066–3075. doi: 10.1016/j.bpj.2010.09.007

Figure 1.

Figure 1

Flow chart of the COMBCON and TASSER_WT algorithms. The COMBCON algorithm is delineated by the dashed lines. A given protein sequence is subject to the four threading algorithms, PROSPECTOR_3.5, PROSPECTOR_4, STITCH_high, and STITCH_low, and the resulting set of contacts are weighted by the total frequency of occurrence in the four methods. These frequency-weighted contacts are then provided to the TASSER_WT structure assembly algorithm along with the set of PROSPECTOR_4-provided template alignments.