Table 3.
Flow Cytometry Cohort subject demographics. SSc‐PAH and SSc without PAH do not have a statistically signifi cant difference in age (p > 0.05). NHW= Non‐Hispanic White; AA= African American; HL= Hispanic Latino; AS= Asian; AI= American Indian. TTE= transthoracic echo; RAP= right atrial pressure; RVSP= right ventricular systolic pressure; TR Jet= tricuspid regurgitant jet. mPAP= mean pulmonary artery pressure, PVR= pulmonary vascular resistance, CO= cardiac output; CI= cardiac index. All values are expressed as mean ± standard deviation.
| Flow cytometry cohort | SSc‐PAH | SSc without PAH | p value |
|---|---|---|---|
| n | 10 | 11 | |
| Age (years) | 59.8 ± 8.0 | 60.1 ± 12.5 | 0.95 |
| Ethnicity (number) | |||
| NHW | 6 | 10 | |
| AA | 2 | 0 | |
| HL | 1 | 0 | |
| AS | 0 | 1 | |
| AI | 1 | 0 | |
| Gender (% female) | 80 | 63.6 | |
| Oral pulmonary hypertension therapy (%) | 100 | n/a | |
| 6 MWD (m) | 304.6 ± 75.5 | ||
| Pulmonary function tests | |||
| FVC (%) | 85.5 ± 20.7 | 90.1 ± 13.9 | 0.57 |
| Dlco (%) | 40.7± 13.9 | 77.3 ± 21.5 | 0.0003 |
| FVC/DLco | 2.2 ± 0.5 | 1.2 ± 0.3 | 6.2 10−5 |
| Transthoracic echo data | |||
| TTE RAP (mmHg) | 7.8 ± 17.7 | 5.3 ± 2.4 | 0.25 |
| TTE RVSP (mmHg) | 68.6 ± 17.7 | 29.1 ± 8.3 | 8.7 × 10−5 |
| TTE TR jet (m/s2) | 3.7 ± 0.3 | 2.4 ± 0.4 | 4.6 × 10−5 |
| Right heart catheterization data | |||
| RAP (mmHg) | 4.9 ± 4.0 | ||
| mPAP (mmHg) | 41.7 ± 9.7 | ||
| PVR (WU) | 8.6 ± 3.6 | ||
| CO (L/min) | 4.4 ± 0.9 | ||
| CI (L/min/m2) | 2.6 ± 0.3 | ||