FIGURE 3.

Oligomeric Aβ attenuates BDNF protein expression during conditioning. Western blots demonstrating that preparations treated by oligomeric Aβ (AβO; 200 nm) for two pairing sessions resulted in suppression of BDNF protein expression are shown, whereas treatment with fibrillar (AβF) or scrambled (AβS) Aβ showed levels of BDNF expression comparable with normal conditioning (C2). Actin loading controls are also shown. % Ps, percentage of pseudoconditioning. Asterisks indicate significant differences from pseudoconditioning (p values under “Results”).