TABLE 9.

Root mean square error after superposition of Cα atoms (in Å)

FSH¹ and FSH² indicate hormone from complexes 1 and 2, respectively, in Protein Data Bank code 1XWD (30); 1FL7¹ and 1FL7² indicate the two independent FSH molecules present in Protein Data Bank code 1FL7 (57); Protein Data Bank code 1HCN is the structure of human CG at 2.6 Å resolution (56); LH indicates modeled structure of LH (this study); TSH indicates the modeled structure of TSH (this paper). 1XWD¹ and 1XWD² indicate ECD from complexes 1 and 2, respectively, in Protein Data Bank code 1XWD (30); LHR indicates the modeled structure of the LHR ECD (this study); Protein Data Bank code 3G04 indicates TSHR ECD from 3 Protein Data Bank code G04 (32).

	FSH1	FSH2	1FL71	1FL72	1HCN	LH	TSH	CG
GpHs
FSH1	X	0.7	1.0	1.6	1.5	0.4	0.3	0.7
FSH2	0.7	X	1.0	1.5	1.6	0.7	0.7	0.8
1FL71	1.0	1.0	X	1.2	1.7	1.2	1.0	0.8
1FL72	1.6	1.5	1.2	X	1.6	1.7	1.6	1.3
1HCN	1.5	1.6	1.7	1.6	X	1.5	1.6	1.8
LH	0.4	0.7	1.2	1.7	1.5	X	0.4	0.7
TSH	0.3	0.7	1.0	1.6	1.6	0.4	X	0.6
CG	0.7	0.8	0.8	1.3	1.8	0.7	0.6	X
ECDs	1XWD1	1XWD2	LHR	3G04
1XWD1	X	0.7	0.4	1.1
1XWD2	0.7	X	0.5	1.2
LHR	0.4	0.5	X	1.1
3G04	1.1	1.2	1.1	X