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. Author manuscript; available in PMC: 2010 Oct 29.
Published in final edited form as: Surgery. 1965 Jul;58:131–155.

Table V.

Homotransplantation with immunosuppression (fate of 24 animals living 50 days or longer; the survival figures for dogs still living is brought up to Feb. 10, 1965)

Group No. dogs Survival (days) Gross cause of death Last bilirubin (mg. %) Last alkaline phosphatase (B.U.*) Last SGOT (S-F.U.)
1 1 324 Alive 0.1 1.9 23
2 98 Pneumonitis; liver failure 5.7 503 760
3 116 Alive 0.3 58 62
4 90 Alive 0.3 172 94
2 1 120 Gastrointestinal hemorrhage; liver failure 3.7 296 870
2 58 Pneumonitis 1.3 300 220
3 228 Alive 0.1 73 470
4 70 Gastrointestinal hemorrhage; liver failure 5.9 516 1660
5 181 Alive 4.1 361 1080
3 1 218 Alive 0.1 30 400
2 101 Pneumonitis; liver failure 5.6 436 580
3 201 Alive 0.1 16 650
4 1 161 Bleeding duodenal ulcer; liver failure 4.7 166 110
2 103 Post biopsy hemorrhage; liver failure 5.7 746 380
5 1 112 Alive 6.2 692 1000
6 1 69 Pneumonitis; liver failure; gastrointestinal hemorrhage 3.9 657 1200
2 50 Pneumonitis; liver failure 4.8 354 250
3 93 Alive 3.9 268 1068
7 1 82 Alive 2.8 527 1900
2 81 Alive 0.2 188 360
3 77 Alive 6.1 184 500
8 1 72 Alive 4.3 530 1100
2 68 Alive 4.4 140 37
3 62 Alive 7.0 473 1500
*

Bodansky units.

Sigma-Frankel units.

Azathioprine stopped after 116 to 123 days; subsequent course without immunosuppression.