Figure 4.

Single burst kinetics of OGG1. OGG1 (25 nM) was reacted with 500 nM 8-oxoG·C substrate for 0.5–8 min. Reactions were terminated as described in Figure 1. Open circles, OGG1 alone; closed circles, OGG1 plus a 5-fold molar excess of APE1. Data points are means of three independent experiments.