Table 2. Affinity of OGG1 and APE1 for repair substrates and products.

Enzyme	Substrate	Kdapp (nM)
OGG1	8-oxoG·C	23.4 ± 3.4
OGG1	AP site	2.8 ± 0.2
OGG1	β-elimination	223 ± 19
OGG1	3′-OH	20.7 ± 2.5
APE1	AP site	1.7 ± 0.2
APE1	β-elimination	72.7 ± 6.6
APE1	3′-OH	4.3 ± 0.5

All duplex oligonucleotides have identical sequences, except for the lesion opposite cytosine.