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Photomicrographs of representative histological sections of the ankle joint from four treatment groups and a healthy control group. A. Click PEG-Dex; B. Healthy; C. Free Dex; D. Saline; E. Click PEG. F. Saline, at higher magnification. Finger-like pannus formation (single arrow), bone destruction (asterisk) and cartilage damage (double arrow) are clearly evident in free Dex, click PEG and saline groups. Bar=0.5 mm in A~E, bar = 0.05mm in F.
