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. 2010 Oct 29;5(10):e13733. doi: 10.1371/journal.pone.0013733

Table 5. Summary of sensitivity and specificity of malaria LAMP assays reported in the literature.

Reference test Poon et al. [16] Paris et al. [15] Han et al. [14] Chen et al. [13] Yamamura et al. [17] RealAmp#
Microscopy (parasitemia)* Not reported Not reported 210–24,164p/µL Not reported 0.06–6.12% parasitemia 61–248960 p/µL
Sensitivity (%) 73.1 94.3 98.3 97.8 96.7
Specificity (%) 100 98.5 100 85.7 91.7
Nested PCR
Sensitivity (%) 95** 76.1/79.1** 98.8
Specificity (%) 99** 89.6/58.3** 100
HRP-II RDT
Sensitivity (%) 77.6
Specificity (%) 100
3

*As reported by the authors.

**In these studies DNA amplification was performed using heat treated whole blood.

#

Results from the current study.