Table 2. Immunogenicity Data for Children 2–17 years.
| Baseline seronegative | All recipients | Children aged 2–9 years | ||||||||||
| Day 0n = 226, 58* | Day 15n = 112, 28* | Day 29n = 114, 30* | Day 57n = 221, 56* | Day 0n = 255, 64* | Day 15n = 129, 32* | Day 29n = 126, 32* | Day 57n = 250, 62* | Day 0n = 144, 30* | Day 15n = 71, 16* | Day 29n = 73, 14* | Day 57n = 143, 30 | |
| GMT | ||||||||||||
| Vaccine | 2.03 | 2.53 | 2.65 | 6.05 | 2.81 | 3.55 | 3.53 | 7.61 | 2.48 | 3.15 | 3.42 | 6.20 |
| Placebo | 2.01 | 2.21 | 2.35 | 3.08 | 2.50 | 2.89 | 2.71 | 3.70 | 2.64 | 3.08 | 2.32 | 3.10 |
| Seroconversion rate, % | ||||||||||||
| Vaccine | NA | 8.9 | 11.4 | 34.8 | NA | 7.8 | 11.1 | 32.0 | NA | 8.5 | 15.1 | 28.0 |
| Placebo | NA | 7.1 | 6.7 | 16.1 | NA | 6.3 | 6.3 | 14.5 | NA | 0 | 0 | 6.7 |
| GMT ≥32, n (%) | ||||||||||||
| Vaccine | 42 (19.0) | 66 (26.4) | 33 (23.1) | |||||||||
| Placebo | 4 (7.1) | 6 (9.7) | 2 (6.7) | |||||||||
| Rate difference, % (95% CI) | 11.9(11.3, 19.6) | 16.7(5.9, 25.2) | 16.4(0.7, 26.6) | |||||||||
GMT = geometric mean titer; NA = not applicable.
*All n's are presented as vaccine, placebo.