Figure 6. Recruitment of immature myeloid cells to parasympathetic ganglia is increased in TGF-β1 transgenic mice.
Panels A and B. Inflammatory lesions demonstrate significantly greater recruitment of CD115+ myeloid cells to parasympathetic neurovascular bundles in transgenic mice (Panel B) compared to wildtype control (Panel A). Panels C and D. Quantitation yields significantly greater CD115+ monocytes in transgenic compared to wildtype parasympathetic ganglia in mice over one year of age (* P<0.05) (Panel C), whereas no significant differences in F4/80 staining is observed (Panel D). All images captured at ×200.
