Table 3. Association p-values of TLR1 tSNPs with severe sepsis complications.
Organ dysfunction | |||||||||
tSNP | Hospital mortality | Acute lung injury | Gram positive infection | Pulmonary infection | Circulatory | Neurologic | Coagulation | Renal | Hepatic |
-7202A/G | 0.306 (0.566) | 0.100 (0.108) | 0.253 (0.110) | 0.129 (0.399) | 0.001 (0.008) | 0.621 (0.618) | 0.464 (0.618) | 0.641 (0.382) | 0.657 (0.982) |
-5531A/G | 0.648 | 0.182 | 0.714 | 0.004 | 0.501 | 0.224 | 0.224 | 0.156 | 0.574 |
-2299C/T | 0.818 | 0.845 | 0.067 | 0.803 | 0.111 | 0.935 | 0.935 | 0.428 | 0.737 |
-2076C/T | 0.327 | 0.405 | 0.738 | 0.004 | 0.551 | 0.372 | 0.372 | 0.273 | 0.941 |
238C/G (Arg80Thr) | 0.080 | 0.181 | 0.622 | 0.151 | 1.000 | 1.000 | 0.861 | 0.642 | 0.363 |
742A/G (Asn248Ser) | 0.530 | 0.090 | 0.438 | 0.037 | 0.009 | 0.481 | 0.481 | 0.986 | 0.671 |
1804G/T (Ser602Ile) | 0.164 (0.208) | 0.142 (0.343) | 0.129 | 0.309 (0.677) | 0.024 | 0.557 | 0.310 | 0.988 | 0.463 |
In parenthesis, p-value for a recessive model; nominal significances in bold.