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. 2010 Oct 17;17(1):82. doi: 10.1186/1423-0127-17-82

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Copyright ©2010 Honig et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cre-mediated recombination in the pancreatic primordium and inner ear in the e10.5 embryo. Whole-mount images of a pdx1-cre^Cre/0; rosa26^LacZ/+embryo (A & B) and a pdx1-cre^0/0; rosa26^LacZ/+embryo (C) processed for β-galactosidase activity. β-galactosidase activity was observed in the pancreatic primordium (bottom arrow, left panel) and inner ear formation (top arrow, A; region in higher magnification in B). β-galactosidase activity was not evident in pdx1-cre^0/0; rosa26^LacZ/+control embryos (C). Scale bars, 1 mm (A and C) and 150 μm (B).