Table 3.
Relative expression of genes involved in the TLR signaling cascade.
| Gene Name | DC | 4T1 | Expression ratiob |
|---|---|---|---|
| TLR4 | 0.049 +/− 0.01a | 0.014 +/− 0.00 | 3.5 |
| CD14 | 0.182 +/− 0.09 | 0.016 +/− 0.00 | 11.4 |
| TIRAP | 0.018 +/− 0.00 | 0.093 +/− 0.02 | 0.2 |
| Myd88 | 0.123 +/− 0.01 | 0.078 +/− 0.01 | 1.6 |
| IRAK4 | 0.013 +/− 0.00 | 0.013 +/− 0.00 | 1.0 |
| TRAF6 | 0.016 +/− 0.00 | 0.008 +/− 0.00 | 2.0 |
| TAKI | 0.003 +/− 0.00 | 0.007 +/− 0.00 | 0.4 |
| NF-kBp50 | 0.191 +/− 0.02 | 0.109 +/− 0.01 | 1.8 |
| NF-kBp65 | 0.049 +/− 0.01 | 0.030 +/− 0.00 | 1.6 |
| MEKK1 | 0.114 +/− 0.02 | 0.047 +/− 0.01 | 2.4 |
| MKK3 | 0.197 +/− 0.02 | 0.618 +/− 0.07 | 0.3 |
| MAPK11 | 0.138 +/− 0.02 | 0.142 +/− 0.02 | 0.9 |
| TRAM | 0.017 +/− 0.00 | 0.005 +/− 0.00 | 3.4 |
| TRIF | 0.004 +/− 0.00 | 0.006 +/− 0.00 | 0.7 |
| TBK1 | 0.045 +/− 0.00 | 0.051 +/− 0.01 | 0.9 |
| IRF3 | 0.006 +/− 0.00 | 0.010 +/− 0.00 | 0.6 |
a
Average and standard error of the integrated density value (IDV) from three separate experiments.
b
Ratio of the IDV from DC/4T1.