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. Author manuscript; available in PMC: 2011 Nov 5.
Published in final edited form as: Org Lett. 2010 Nov 5;12(21):4936–4939. doi: 10.1021/ol1022036

Table 3.

One-pot, three-step synthesis of 1-substituted 4-acyl-1H-1,2,3-triazoles 7a-e

graphic file with name nihms-245231-t0005.jpg

entry Ar R method Aa
yield (%)
method Bb
yield (%)

1 Ph Bn 40 42
2 4-MeO-C6H4 Bn 80 83
3 4-F-C6H4 Bn 82 88
4 4-NO2-C6H4 Bn 32 36
5 2-Me-C6H4 Bn 35 34
a

A mixture of TBAF (1.0 M, 2.0 equiv) and CuI (10 mol %) was used

b

CuF2 (2.0 equiv) was used.