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. Author manuscript; available in PMC: 2011 Nov 12.
Published in final edited form as: J Mol Biol. 2010 Aug 13;403(5):777–802. doi: 10.1016/j.jmb.2010.07.057

Figure 1.

Figure 1

Mesoscale model of the basic chromatin building block. The nucleosome core surface with wrapped DNA without histone tails is modeled as an irregularly shaped rigid body with 300 optimized pseudo surface charges (smallest white, pink, magenta, and blue spheres). The linker DNA (large red spheres) is treated using the discrete worm like chain model. The histone tails are coarse grained as bead models (red, yellow, green, and blue medium spheres). The LH is modeled as 3 charged beads rigidly connected to the nucleosome (turquoise spheres).