Table 1.
Donor characteristics and processing data from 33 clinical islet preparations. For some parameters, data from only 32 preparations are presented, as noted.
| Characteristic | Mean±SEM | Range | N |
|---|---|---|---|
| Donor age | 51.5 ± 1.5 | 31-67 | |
| Donor BMI | 28.7 ± 1.0 | 21.4 - 47.6 | |
| Duration acute Illness (hr) | 37.6 ± 5.9 | 1-129 | |
| Duration brain death (hr) | 15.7 ± 1.1 | 0.7-27 | |
| Cold ischemia time (hr) | 7.5 ± 0.5 | 4-16.3 | |
| Pancreatic weight (g) | 85.5 ± 3.8 | 45-144 | |
| Digestion time (min) | 19.6 ± 0.7 | 12-28 | |
| Undigested tissue remaining (g) | 25.2 ± 2.6 | 2-65 | 32 |
| Packed cell volume (ml) | |||
| Total tissue recovered in all fractions | 42.7 ± 2.5 | 18-92 | |
| Final islet pellet | 1.81 ± 0.19 | 0.60-5.0 | |
| Fraction of islets with impermeable membranes (% PI negative) | 90 ± 1 | 80-95 | 32 |
| Islet equivalents by | 3.27 ± 1.55 × 105 | (2.43 – 8.14) × 105 | |
| DTZ staining (NIE)DTZ |