Table 2.
Comparisons of agreement between US white, North Indian, and South Indian reference standards in the diagnosis of osteoporosis and osteopenia in South Asian Indians residing in the United States
| A. Total Hip, US White versus South Indian | B. Total Hip, US White versus North Indian | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Count (%)a | South Indian | Count (%) | North Indian | ||||||
| Normal | Osteopenia | Osteoporosis | Normal | Osteopenia | Osteoporosis | ||||
| US White | Normal | 114 (76) | 0 (0) | 0 (0) | US White | Normal | 114 (76) | 0 (0) | 0 (0) |
| Osteopenia | 28 (19) | 6 (4) | 0 (0) | Osteopenia | 18 (12) | 16 (11) | 0 (0) | ||
| Osteoporosis | 0 (0) | 1 (1) | 1 (1) | Osteoporosis | 0 (0) | 1 (1) | 1 (1) | ||
| % reclassifiedb = 19% (95% CI, 14–25%) | % reclassified = 13% (95% CI, 7–18%) | ||||||||
| Mean T- score differencec = 1.26 (95% CI, 1.22–1.30) | Mean T-score difference = 0.81 (95% CI, 0.75 – 0.86) | ||||||||
| C. Total Hip, North Indian versus South Indian | D. Lumbar Spine, US White versus South Indian | ||||||||
| Count (%) | South Indian | Count (%) | South Indian | ||||||
| Normal | Osteopenia | Osteoporosis | Normal | Osteopenia | Osteoporosis | ||||
| North Indian | Normal | 132 (88) | 0 (0) | 0 (0) | US White | Normal | 75(50) | 0 (0) | 0 (0) |
| Osteopenia | 10 (7) | 7 (6) | 0 (0) | Osteopenia | 46 (31) | 11 (7) | 0 (0) | ||
| Osteoporosis | 0 (0) | 0 (0) | 1 (1) | Osteoporosis | 0 (0) | 14 (9) | 4 (3) | ||
| % reclassified = 7% (95% CI = 3–12%) | % reclassified = 40% (95% CI = 32–48%) | ||||||||
| Mean T-score difference = 0.45 (95% CI = 0.38–0.51) | Mean T-score difference 1.09 (95% CI, 1.08–1.09) | ||||||||
Due to rounding error percentages may not sum to 100%, and individual percents of reclassified individuals may not sum to the total % reclassified.
% reclassified and mean T-score difference are, respectively the percentage of individuals whose BMD category assignment changed, and mean change in T-score, that resulted from switching between a given pair of reference standards.