Table 2. Detailed information on the FAP adenoma samples used in the methylation and expression analyses.
FAP adenoma | Expr | Meth | Sex M/F | Age in years | Site of biopsy – right/left side of colon (ND) | Size of adenoma (mm) | Pathology (TA/TVA) | Grade of dysplasia (low/high) |
---|---|---|---|---|---|---|---|---|
1a | Y | Y | F | 32 | L | 2 | TA | Low |
1b | Y | Y | L | 2 | TA | Low | ||
1c | Y | Y | L | 2 | TA | Low | ||
1d | Y | Y | L | 2 | TA | Low | ||
2a | Y | N | F | 29 | R | 5 | TA | Low |
2b | Y | N | L | 5 | TA | Low | ||
2c | Y | N | L | 5 | TA | Low | ||
3a | Y | Y | M | 20 | L | 5 | TA | Low |
3b | Y | Y | R | 5 | TVA | High | ||
3c | Y | Y | L | 35 | TA | Low | ||
4a | Y | N | F | 26 | R | 6 | TA | Low |
4b | Y | N | L | 9 | TA | Low | ||
5a | Y | Y | F | 26 | R | 3 | TA | Low |
5b | Y | Y | R | 3 | TA | Low | ||
6a | Y | N | M | 21 | ND | 2 | TA | Low |
7a | Y | Y | F | 23 | ND | 5 | TA | Low |
8a | Y | Y | M | 20 | ND | 3 | TA | Low |
9a | Y | Y | M | 19 | R | 5 | TA | Low |
10a | Y | Y | M | 19 | ND | 3 | TA | Low |
11a | Y | Y | F | 36 | R | 2 | TA | Low |
11b | Y | Y | R | 2 | TA | Low | ||
11c | Y | Y | L | 2 | TA | Low | ||
11d | Y | Y | L | 3 | TA | Low | ||
12a | Y | Y | M | 38 | L | 2 | TA | Low |
13a | Y | Y | F | 27 | ND | 5 | TA | Low |
14a | Y | Y | F | 35 | L | 10 | TA | Low |
15 | N | Y | F | 25 | ND | 5 | TA | Low |
16 | N | Y | M | 18 | L | 10 | TA | Low |
17 | N | Y | M | 18 | R | 5 | TA | Low |
18 | N | Y | M | 19 | L | 7 | TA | Low |
Abbreviations: ND=not documented; FAP=familial adenomatous polyposis; Expr=mRNA expression analysis performed; Meth=methylation analysis performed; M=male; F=female; TA=tubular adenoma; TVA=tubular villus adenoma.