Table 4. P-values (Wilcoxon's rank-sum test) of methylation at each of the seven CpG sites tested in sFRP1 in adenoma vs matched normal mucosa in both FAP and sporadic patients.
CpG site | FAP (n=14) | Sporadic (n=19) |
---|---|---|
1 | 0.217 | 0.007 |
2 | 0.367 | 0.006 |
3 | 0.075 | 0.007 |
4 | 0.096 | 0.016 |
5 | 0.451 | 0.005 |
6 | 0.975 | 0.016 |
7 | 0.221 | 0.015 |
Average of site 3 and 4 | 0.030 | 0.010 |
Average of site 1 to 7 | 0.119 | 0.003 |
Abbreviation: FAP=familial adenomatous polyposis.