Table 2. Expressions of EGFR family and genetic mutations of the patients with endometrial cancer.
|
PTEN (n=45)
|
PIK3CA (n=45)
|
KRAS (n=45)
|
||||
|---|---|---|---|---|---|---|
| MT (n=18) | WT (n=27) | MT (n=7) | WT (n=38) | MT (n=10) | WT (n=35) | |
| EGFR expression | ||||||
| Low (n=26) | 10 | 16 | 6 | 20 | 7 | 19 |
| High (n=19) | 8 | 11 | 1 | 18 | 3 | 16 |
| P-value | 0.8053 | 0.1034 | 0.3749 | |||
| HER-2 expression | ||||||
| Low (n=28) | 14 | 14 | 5 | 23 | 7 | 21 |
| High (n=17) | 4 | 13 | 2 | 15 | 3 | 14 |
| P-value | 0.0789 | 0.5846 | 0.5651 | |||
| HER-4 expression | ||||||
| Low (n=28) | 11 | 17 | 6 | 22 | 7 | 21 |
| High (n=17) | 7 | 10 | 1 | 16 | 3 | 14 |
| P-value | 0.9001 | 0.1630 | 0.5651 | |||
Abbreviations: EGFR=epidermal growth factor receptor; HER-2=human epidermal growth factor receptor-2; MT=mutation; WT=wild type.