. 2010 Aug 17;103(6):899–909. doi: 10.1038/sj.bjc.6605829

Table 4. The interrelationships between Src kinase family member expression and Ki67.

Total patient cohort (274 patients)		χ² P-values
Variables	Numbers	c-Src cyto	c-Src memb	Lyn nuc	Lyn cyto	Lyn memb	Lck nuc	Lck cyto	Lck memb	Ki67
c-Src nuc (positive/negative)	129/145	<0.001	<0.001	0.163	0.646	0.917	0.328	0.461	0.701	0.001
c-Src cyto (positive/negative)	118/156		<0.001	0.621	0.579	0.780	0.299	0.508	0.934	0.110
c-Src memb (positive/negative)	113/161			0.691	0.497	0.410	0.274	0.064	0.017	0.110
Lyn nuclear (positive/negative)	66/116				<0.001	0.345	0.016	0.975	0.534	0.081
Lyn cyto (positive/negative)	61/121					<0.001	0.424	0.067	0.032	0.598
Lyn memb (positive/negative)	9/173						0.282	0.726	0.053	0.010
Lck nuclear (positive/negative)	116/158							<0.001	0.001	0.045
Lck cyto (positive/negative)	117/157								<0.001	0.572
Lck memb (positive/negative)	14/260									0.506

Abbreviations: c-Src=total Src kinase; c-Src cyto=c-Src cytoplasmic expression; c-Src memb=c-Src membrane expression; duct=ductal carcinoma; c-Src nuc=c-Src nuclear expression; Grade=Bloom and Richardson grade; Ki67=Ki67 proliferation score low<5, moderate 5–20, high >20; Lck cyto=Lck cytoplasmic expression; Lck memb=Lck membrane expression; Lck nuc=Lyn nuclear expression; lob=lobular carcinoma; tub=tubular carcinoma; Lyn cyto=Lyn cytoplasmic expression; Lyn memb=Lyn membrane expression; Lyn nuc=Lyn nuclear expression; others=mucinous, mucoid and micropapillary carcinoma.

Bold typeface is used to highlight significant P-value.