Figure 2.

Histopathological correlation with the lesional age of secondary syphilitic skin eruptions. Histopathological changes are displayed analogous to clinical alterations in four groups according to lesional persistence. Representative pictures with a magnification ×100 and ×400 are shown for lesional persistence of four different times: (A) 0–10 days (n = 6), (B) 11–20 days (n = 6), (C) 21–30 days (n = 7), and (D) more than 30 days (n = 6). Quantifications of epidermal and dermal alterations are shown in E–H.