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. 2010 Nov;177(5):2421–2432. doi: 10.2353/ajpath.2010.100277

Figure 6.

Figure 6

CD8+ T-cells as the main source of IFN-γ and IL-17. Triple immunofluorescence labeling of syphilitic lesions from HIV-infected and HIV− patients with anti-CD3 (FITC), anti-CD8 (APC), and (A) anti–IFN-γ (TRITC), or (B) anti–IL-17 (TRITC) reveals that CD8-positive T-cells are IFN-γ– and IL-17–producing cells. C: Double labeling of IFN-γ and IL-17 showed an overlapping staining pattern. A–C: Arrows denote triple-positive cells. Original magnification, ×400. D: Data are given as the absolute numbers of positive cells ± SEM.