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Unilateral dorsal root avulsion leads to bilateral below-level mechanical allodynia. Following baseline assessment of the response to calibrated von Frey filaments, the rats underwent avulsion surgery. Avulsion of T13 + L1 induced ipsilateral and contralateral hindpaw mechanical allodynia that became robust within 21 days post-surgery (n = 6 per group; A, ipsilateral; B, contralateral; *p < 0.05 compared to sham animals; BL, baseline).
