Table 3.

Unadjusted Relationship between Age, Fertility Characteristics, Treatments, and the Monthly Likelihood of Achieving a Pregnancy

		N	HR	95% CI		P-Value	Overall P-Value
Female age	<35	162	1.00	ref		ref
	35–39	156	0.78	0.58	1.03	0.08
	≥ 40	89	0.29	0.18	0.45	<0.001	<0.001
Male age	<35	126	1.00	ref		ref
	35–39	129	0.70	0.51	0.97	0.03
	≥40	101	0.56	0.39	0.81	<0.001
	Unknown	52	0.53	0.33	0.84	0.01	0.004
Prior children	No	309	1.00	ref		ref
	Yes	97	1.10	0.81	1.50	0.53	0.53
Prior pregnancy	0	193	1.00	ref		ref
	1	92	1.15	.82	1.62	.40
	2	64	1.22	.83	1.81	.30
	3+	40	.81	.49	1.32	.39	.41
Prior fertility treatment	Oral medications	251	1.05	0.79	1.40	0.74	0.74
	Injectable medications	94	1.26	0.92	1.71	0.15	0.15
	IUI	139	1.04	0.79	1.40	0.74	0.74
Duration of infertility	< 1 year	69	1.00	ref		ref
	1–2 years	158	1.30	0.88	1.92	0.18
	≥ 2 years	152	0.89	0.59	1.33	0.56
	Unknown	29	0.69	0.35	1.37	0.29	0.03
Couple fertility diagnosis	No known infertility factors	18	1.00	ref		ref
	Male factor only	29	0.67	0.34	1.34	0.26
	Female factor only	238	0.45	0.26	0.78	0.01
	Male and female factors	123	0.36	0.20	0.64	<0.001	0.002
Female diagnosis	Tubal	57	0.94	0.64	1.40	0.77	0.77
	Uterine	48	0.77	0.49	1.21	0.26	0.26
	Ovarian	155	0.60	0.45	0.81	<0.001	<0.001
	Ovulatory	109	1.29	0.96	1.73	0.09	0.09
Any cycle-based treatment	No	86	1.00	ref		ref
	Yes	322	2.28	1.51	3.43	<0.001	<0.001
Medications only	No cycle based treatment	86	1.00	ref		ref
	1–2 cycles	9	5.39	2.39	12.16	<0.001
	3+ cycles	6	0.87	0.20	3.67	0.85	<0.001
Intrauterine insemination only	No cycle based treatment	86	1.00	ref		ref
	1 cycle	33	3.14	1.81	5.44	<0.001
	2 cycles	23	2.93	1.52	5.62	<0.001
	3 cycles	15	3.12	1.53	6.34	<0.001
	4+ cycles	20	1.63	0.79	3.39	0.19	<0.001
In vitro fertilization only	No cycle based treatment	86	1.00	ref		ref
	1 cycle	83	2.46	1.52	3.98	<0.001
	2 cycles	57	2.45	1.47	4.07	0.001
	3+ cycles	52	1.49	0.85	2.59	0.16	<0.001