Table 2.
Anthropometric parameters, iron status and inflammatory markers in ESRD and control population
| Characteristic | ESRD n = 74 | Controls n = 52 | P value |
|---|---|---|---|
| Waist:Hip ratio | 0.88 ± 0.11 | 0.95 ± 0.04 | <0.001 |
| Σ skin fold thickness (mm) | 24 ± 10.1 | 60.4 ± 25.6 | <0.0001 |
| Body fat percent (%) | 12.8 ± 6.1 | 27.0 ± 5.8 | <0.0001 |
| MAMC (cm) | 22.7 ± 3.3 | 25.2 ± 3.2 | <0.0001 |
| Serum albumin (g/dl) | 2.96 ± 0.06 | 4.16 ± 0.06 | <0.0001 |
| Hemoglobin (g/dl) | 8.1 ± 0.2 | 13.8 ± 0.2 | <0.0001 |
| Iron (microgm/dl) | 153.4 ± 31.6 | 100.3 ± 6.7 | 0.78 |
| TSAT (percent) | 32.2 ± 2.3 | 22.5 ± 1.5 | 0.007 |
| Serum ferritin (ng/ml) | 331.7 ± 39.56 | 28.3 ± 4.1 | <0.001 |
| Serum CRP (mg/l) | 35.8 ± 3.4 | 1.01 ± 0.06 | <0.00 |
| Interleukin-6 (pg/ml) | 29.6 ± 3.04 | 15.7 ± 1.05 | <0.001 |
| TNF-α (pg/ml) | 43.1 ± 2.7 | 20.7 ± 1.4 | <0.001 |
| Hepcidin (ng/ml) | 332.2 ± 17.5 | 241.9 ± 18.4 | 0.01 |
(BMI-Body mass index, Σ Skin fold thickness – sum of the triceps, biceps, subscapular, and suprailiac skin fold thicknesses, MAMC – mid-arm muscle circumference, TSAT- Transferrin saturation, CRP – C reactive protein, TNF-α - Tumor necrosis factor alpha)