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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: Circ Res. 2010 Aug 12;107(8):10.1161/CIRCRESAHA.110.220764. doi: 10.1161/CIRCRESAHA.110.220764

Figure 4.

Figure 4

GATA6 is required for the AngII/PE induced cardiac hypertrophy response. A, VW/BW after 2 weeks of vehicle (Veh) or AngII/PE infusion using osmotic minipumps. *P<0.05 vs Gata6fl/fl Veh.; †P<0.05 vs Gata6fl/fl AngII/PE. B, Cardiac FS% from vehicle and Ang/PE infused mice. *P<0.05 vs Gata6fl/fl AngII/PE. C, Left ventricular end diastolic dimension (LVED) after 2 weeks of Veh or AngII/PE infusion. *P<0.05 vs Gata6fl/fl AngII/PE. D, Taqman qPCR for expression of ANF mRNA in Veh and AngII/PE infused mice. *P<0.05 vs Gata6fl/fl AngII/PE. E, Taqman qPCR for expression of αMHC mRNA in Veh and AngII/PE infused mice. *P<0.05 vs Gata6fl/fl Veh. F, Taqman qPCR for expression of skeletal α-actin mRNA in Veh and AngII/PE infused mice. *P<0.05 vs Gata6fl/fl AngII/PE.