Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Sep 14;103(8):1182–1191. doi: 10.1038/sj.bjc.6605881

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2010 Cancer Research UK

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

The effect of dietary LA on the invasion ability of OCUM-2MD3 cells through Matrigel. (A) Growth of OCUM-2MD3 cell lines after LA treatment. As described in the Materials and methods section, the number of viable OCUM-2MD3 cells with or without 30 μM of LA treatment for the indicated time period was determined. (B) Apoptosis induction by LA. Upper panel: the typical examples of flowcytometic analysis in OCUM-2MD3 cells treated with vehicle (ethanol); apoptosis rate was 0.9%. Lower panel: analysis of cells treated with 30 μM of LA; apoptosis rate was 0.0%. (C) Cells were treated for 45 min with vehicle (ethanol) or the indicated concentration of LA. Invasion across Matrigel-coated membranes was assessed after 72 h. a: Different from 0 μM LA (P<0.01). b: Different from 3 and 10 μM LA (P<0.05). (D) Cells were treated with ethanol (dotted line) or 30 μM LA (solid line) and allowed to invade for the indicated time periods. a: Different from the ethanol-treated sample at the same time (P<0.05). (E) OCUM-12, NUGC3 and MKN-45 cells were treated with ethanol (dotted line) or 30 μM LA (solid line). Invasion across Matrigel-coated membranes was assessed after 72 h. a: Different from 0 μM LA (P<0.01). Values shown are mean±s.d. (n=4).