Table 1. Recurrent amplicons observed in the primary tumour and maintained in at least two passages of the xenograft.
Cytogenetic region | Start position * | End position* | Candidate genes | Maximum xenograft ratio (passage) |
---|---|---|---|---|
1q23.3–24.1 | 163.3 | 164.3 | LMX1A, RXRG, LRRC52, MGST3, ALDH9A1, TMCO1, UCK2 | 2.1 (p8) |
7q31.1 | 111.0 | 112.4 | DOCK4, IFRD1, NPM1P14, TMEM168 | 2.2 (p0) |
8p11.21 | 41.6 | 42.2 | MIRN486, ANK1, MYST3, AP3M2, PLAT, IKBKB | 2.12 (p8) |
13q14.11–12 | 43.0 | 44.6 | CCDC122, TSC22D1, NUFIP1 | 2.69 (p0) |
18q11.2–12.1 | 19.6 | 24.3 | CABYR, OSBPL1A, HRH4, RAC1P1, hCG1643695, SS18, PSMA8, TAF4B, KCTD1, hCG38400, AQP4, CHST9, CDH2 | 3.3 (p0) |
UCSC Genome Browser on Human May Assembly; positions are given in megabased.