Table 3. Multivariate analysis of death events (model 1: Beclin 1 and histopathological variables; model 2: significant variables of model 1 including hypoxia variables).

	Model 1		Model 2
Variable	t ratio	P-value	t ratio	P-value
Nodal involvement	4.04	<0.0001	4.89	<0.0001
Grade (2/3 vs 1)	0.09	0.92	—	—
Vascular (yes vs no)	3.13	0.002	2.71	0.007
Necrosis (yeas vs no)	0.03	0.30	—	—
Beclin 1cytoplasmic	5.05	<0.0001	4.97	<0.0001
Beclin 1 nuclear	0.08	0.93	—	—
LDH5	—	—	4.18	<0.0001
HIF1α	—	—	0.69	0.48