Table 1. Patient characteristics.
Pat. No. | Age | Type | T-Stage | N-Stage | ER | PRa | HER -2 | Grading | Response | Response group | |
---|---|---|---|---|---|---|---|---|---|---|---|
Discovery set | 1 | 61 | Lobular | 4b | + | + | + | − | 2 | SD | NR |
2 | 41 | Ductal | 4b | − | − | − | − | 3 | PR | R | |
3 | 52 | Ductal | 3 | − | + | − | − | 3 | pCR | R | |
4 | 30 | Ductal | 3 | + | − | − | Amplified | 2 | PR | R | |
5 | 56 | Lobular | 3 | + | + | − | − | 2 | PR | R | |
6 | 74 | Lobular | 2 | + | + | + | − | 3 | SD | NR | |
7 | 51 | Ductal | 2 | − | − | − | − | 3 | PR | R | |
8 | 68 | Ductal | 2 | − | − | − | − | 3 | pCR | R | |
9 | 37 | Ductal | 2 | − | − | − | − | 3 | SD | NR | |
10 | 46 | Lobular | 2 | + | + | − | − | 3 | SD | NR | |
11 | 52 | Ductal | 2 | + | − | − | − | 3 | SD | NR | |
12 | 60 | Ductal | 3 | + | + | − | − | 1 | PD | NR | |
Validation set | 13 | 51 | Ductal | 2 | − | − | − | − | 3 | PCR | R |
14 | 53 | Ductal | 2 | + | − | − | − | 3 | PR | R | |
15 | 62 | Ductal | 2 | − | + | + | − | 2 | PR | R | |
16 | 51 | Ductal | 2 | + | − | − | − | 3 | SD | NR | |
17 | 48 | Ductal | 3 | − | + | + | Amplified | 2 | PCR | R | |
18 | 40 | Ductal | 2 | + | + | + | − | 2 | SD | NR | |
19 | 30 | Ductal | 2 | − | − | − | − | 3 | SD | NR | |
20 | 59 | Lobular | 2 | + | + | + | − | 2 | SD | NR | |
21 | 66 | Ductal | 2 | + | − | − | − | 3 | PR | R | |
22 | 58 | Lobular | 3 | + | + | − | Amplified | 2 | PR | R | |
23 | 50 | Lobular | 2 | + | + | − | − | 2 | SD | NR | |
24 | 52 | Ductal | 2 | + | + | + | − | 2 | PD | NR | |
25 | 38 | Ductal | 2 | − | + | + | − | 3 | SD | NR |
Abbreviations: ER=oestrogen receptor; HER-2=human epidermal growth factor receptor; pCR=complete pathological remission; PD=progressive disease; NR=nonresponder; PR=partial remission; R=responder; SD=stable disease.
Progesterone receptor.