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Specific hydrolysis of 2-OH-rATP by MTH1. (A) 5 µM of nucleotide substrates incubated with various amounts of MTH1 at 30°C for 5 min. (B) Expanded view of (A) at low concentrations of MTH1. Only the data for 8-OH-dGTP, 2-OH-rATP and dGTP are shown.
