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. Author manuscript; available in PMC: 2011 Mar 23.
Published in final edited form as: Nat Protoc. 2010 Sep 23;5(10):1652–1658. doi: 10.1038/nprot.2010.125

Figure 1.

Figure 1

Schematic representation of the O-deethylation of 7-EFC to produce 7-HFC (ex. 410 nm and em. 510 nm), which is catalyzed by a number of human P450s including CYP 1A2, 2B6, 2C19, 2D6, 2E1, and 3A4.