. Author manuscript; available in PMC: 2010 Nov 1.

Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2009 Jun 18;81(2-3):119–123. doi: 10.1016/j.plefa.2009.05.021

Table 2.

DHA synthesis rates from α-LNA by liver but not by brain exceed brain consumption rates with each of three diets. Data from (16, 29, 36, 37, 52).

Diet during 15 weeks post-wearing	C_brain (DHA) [C_brian (α-LNA)]	c_plasma(DHA) [c_plasma(α-LNA)]	Estimated rate DHA consumption by 1.5 g brain, J_in	Estimated rate DHA formation from α-LNA by 1.5 g brain,	Estimated rate DHA secretion by 11.5 g liver
	μmol/g	nmol/ml	μmol/day	μmol/day	μmol/day
High DHA, fishmeal containing NIH-31-18-4 diet (2.3% FA)	17.6 ± 0.3^#[0.010 ± 0.002]	26 ± 12 [14 ± 13]	0.23	0.002	1.57
High α-LNA diet (4.6% FA); no DHA	11.4 ± 0.8 [0.16 ± 0.003]	6.5 ± 2.6 [27 ± 6]	0.29	0.0016	2.19
Low α-LNA diet (0.2% FA); no DHA	7.14 ± 0.24 [ND]	0.23 ± 0.10 [1.0 ± 0.45]	0.06	0.0000006	0.82

Mean ± SD; FA = fatty acid; ND, not detected.