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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Clin Psychopharmacol. 2010 Aug;30(4):404–410. doi: 10.1097/JCP.0b013e3181e66a62

Figure 2. Visual predictive check for lithium plasma concentration versus time profiles.

Figure 2

The plots show the measured concentrations, the 80% prediction interval [10th – 90th percentile] and the interquartile range [25th – 75th percentile] based on the model including fat-free mass as a covariate. Lines are 10%, 25%, 50%, 75%, 90% percentiles of the predicted concentrations. The markers close to the x-axis represent concentrations below the quantification limit (BQL). At 12 and 24 h many subjects had BQL concentrations (below 0.20 or 0.25 mEq/L) which were taken into account in the model.