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. Author manuscript; available in PMC: 2011 Nov 5.
Published in final edited form as: Org Lett. 2010 Nov 5;12(21):4728–4731. doi: 10.1021/ol102194c

Table 3.

Intramolecular Coupling Reactions.a,b

graphic file with name nihms241424u4.jpg
entry R R′ n product yield (%)
1 H H 1 41 66
2 Me 1 42 73
3 Et 1 43 70
4 H 0 44 15c
5 4-F H 1 45 47
6 Et 1 46 68
7 4-Cl H 1 47 62
8 Me 1 48 65
9 4-CF3 H 1 49 51
10 Me 1 50 59
11 4-Ph Me 1 51 74
a

Conditions: Aryltrimethylsilane (100 μmol), Selectfluor (200 μmol), 5 mol % dppm(AuBr)2, 0.1 M in CH3CN/R′OH (10/1), 50 °C for 14 h.

b

Catalyst addition in two portions over two hours.

c

Yield based on 1H NMR versus nitrobenzene as internal standard.