Fig. 6. Treatment of established virus infection with α-Galcer.

2μg α-Galcer or vehicle were given / animal before infection (Day -1) or on days 1 - 3 of EMCV-D infection of Balb/c mice as shown. Infected animals were monitored for disease as in Fig. 3, with lines indicating abnormal value limits. Results show individual animal glucose tolerance test results (A.) and paralysis scores (B.), measured on day 7 post-infection with % incidence of abnormal glucose results or paralysis. Normoglycemic values were defined as within 3 times the S.D. of the mean value of PBS injected uninfected controls.