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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: J Cell Biochem. 2010 Aug 1;110(5):1073–1081. doi: 10.1002/jcb.22619

Figure 1. Schema of experimental model of heat treatment (A) and effect of hyperthermia, TRAIL, or hyperthermia in combination with TRAIL on growth of CX-1 xenograft (B).

Figure 1

Figure 1

(A) Heating of tumors at a mild hyperthermic temperature (42°C) for 1 hr was performed using water bath immersion of the tumor-bearing right leg. (B) TRAIL was injected into the subcutaneous tumors of mice once they were approximately 50 mm3 in tumor volume. Tumors were exposed to hyperthermic conditions as well as treated with and without TRAIL. Tumors were measured every three days. Error bars represent standard error of the mean from five mice. Asterisk * represents a statistically significant difference between control and hyperthermia alone, TRAIL alone, or hyperthermia in combination with TRAIL at P<0.05.