Table 5.
Estimated frequencies of HLA-B8, DR13, DR4 and DR3 extended haplotypes in African American patients with PSC and ALD listed for liver transplantation. With the exception of the B8-DR3 haplotype only extended B-DR haplotypes with a frequency ≥1% in PSC patients or ALD controls are shown in detail (others combined at either locus).
| HLA-B allele | HLA-DR allele | Frequency in PSC | Frequency in ALD |
|---|---|---|---|
| 8 | 3 | 0.003 | 0.0004 |
| 8 | 13 | 0.011 | 0.004 |
| 8 | 15 | 0.010 | 0.000 |
| 8 | Other DR combined | 0.025 | 0.009 |
| 7 | 13 | 0.020 | 0.016 |
| 35 | 13 | 0.011 | 0.004 |
| 42 | 13 | 0.026 | 0.022 |
| 44 | 13 | 0.022 | 0.011 |
| 45 | 13 | 0.017 | 0.006 |
| 49 | 13 | 0.012 | 0.014 |
| 51 | 13 | 0.013 | 0.000 |
| 53 | 13 | 0.017 | 0.020 |
| 58 | 13 | 0.037 | 0.002 |
| 70 | 13 | 0.017 | 0.007 |
| Other B combined | 13 | 0.076 | 0.053 |
| 44 | 4 | 0.005 | 0.013 |
| 51 | 4 | 0.000 | 0.016 |
| Other B combined | 4 | 0.015 | 0.043 |
| 27 | 3 | 0.000 | 0.010 |
| 42 | 3 | 0.004 | 0.023 |
| Other B combined | 3 | 0.032 | 0.021 |