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. 2010 Nov 1;5(11):e13788. doi: 10.1371/journal.pone.0013788

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Sanz-Arigita et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(a) Matrix of significant differences of synchronization between AD and controls (2-tail t-test, p<0.05 uncorrected). The white and black dots represent brain areas pairs with increased and decreased synchronization in AD respectively. (b-d) A subset of connectional differences corresponding to the matrix (a) are plotted at 3 superior-to-inferior levels through the AAL brain template: (b) = z53; (c) = z73; (d) = z111. Lines depict synchronization between pairs of regions: solid lines = enhanced synchronization; dashed lines = reduced synchronization. Note the pattern of generalized posterior (parietal and occipital) synchronization reductions and increased frontal synchronization.