Table 1. Average synchronization, cluster coefficient and path lengths.

			AD			OC		p values
	Reg_#ROIs	mean		sd	mean		sd
S	Ss_116	0,09		0,01	0,09		0,02	0,82
	Ss_90	0,10	±	0,02	0,10	±	0,02	0,82
	Ms_90	0,09		0,02	0,09		0,02	0,83
γ	Ss_116	4,44		0,50	4,38		0,50	0,69
	Ss_90	3,63	±	0,47	3,64	±	0,38	0,98
	Ms_90	3,72		0,39	3,57		0,30	0,19
Λ	Ss_116	1,53		0,15	1,69		0,22	0,01*
	Ss_90	1,43	±	0,17	1,61	±	0,25	0,01*
	Ms_90	1,44		0,14	1,61		0,27	0,02*

Data are presented as mean ± sd. AD, Alzheimer patient; OC, age-matched control; t-test (2-tailed;

*, p<0.05 between groups difference). While maintaining similar brain average synchronization levels (S), the Alzheimer group consistently shows a significantly shorter corrected path length (λ) that controls and similar cluster coefficient (γ) regardless of the registration procedure (Ss – standard space; Ms – midspace) and the inclusion of cerebellar regions (#ROIs 116 – including cerebellum; #ROIs 90 – excluding cerebellum). All small-world parameters were calculated at K = 10 and synchronization threshold T = 0.05.